Jim Zhao

Lei Xu1
Kristin Brosofsky1
1Lei Xu
1Kristin Brosofsky
1Jonathan Q. Tran
1Jitesh Rana
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OBJECTIVE To evaluate the safety, tolerability, and pharmacokinetics (PK) of BIIB033 (anti-LINGO-1 monoclonal antibody) in healthy volunteers and participants with multiple sclerosis (MS). METHODS In 2 separate randomized, placebo-controlled studies, single ascending doses (SAD; 0.1-100 mg/kg) of BIIB033 or placebo were administered via IV infusion or(More)
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