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Receptor interacting protein 140 (RIP140) interacts with retinoic acid receptor (RAR) and retinoid X receptor (RXR) constitutively, but hormone binding enhances this interaction. The ligand-independent interaction is mediated by the amino and central regions of RIP140 which contain a total of nine copies of the LXXLL motif, whereas the agonist-induced(More)
PURPOSE The purpose was to investigate vitrification of human blastocysts using the cryoloop. METHODS Thirteen couples elected to have blastocysts cryopreserved via vitrification (N = 54 blastocysts). Embryos were exposed to two vitrification solutions, pipetted onto the cryoloop then plunged into liquid nitrogen. On the day of embryo replacement,(More)
CONTEXT Aperio Technologies, Inc (Vista, California) provides a new immunohistochemistry (IHC) HER2 Image Analysis (IA) system that allows tuning of the intensity thresholds of the HER2/ neu scoring scheme to adapt to the staining characteristics of different reagents. OBJECTIVE To compare the trainable IHC HER2 IA system for different reagents to(More)
The performance of a novel dry powder inhaler designed to deliver exceptionally high doses was investigated using pumactant as a model powder. Pumactant (a synthetic lung surfactant consisting of a phospholipid mixture), with a 90th percentile particle size of 2.92 microm is highly cohesive, has a high moisture affinity (6.2% w/w at 45% RH), and is(More)
Can J Emerg Med 2003;5(5):343-7 These Recommendations were approved by the CAEP Board June 8, 2003. *Chief, Schwartz–Reisman Emergency Centre, Mount Sinai Hospital, Toronto, Ont.; and Assistant Professor, Department of Family and Community Medicine, University of Toronto, Toronto, Ont. †Chief, Emergency Department, Queen Elizabeth Hospital, Charlottetown,(More)
OBJECTIVES Describe health-related quality of life (HRQoL) of former Canadian Forces (CF) men and women in uniform (Veterans) after transition to civilian life, and compare to age- and sex-adjusted Canadian norms. METHODS The 2010 Survey on Transition to Civilian Life was a national computer-assisted telephone survey of CF Regular Force personnel who(More)
Management Ministerial Council. While reasonable efforts have been made to ensure that the contents of this publication are factually correct, the Australian Government and members of the Natural Resource Management Ministerial Council (or the governments that the council members represent) do not accept responsibility for the accuracy or completeness of(More)