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1: Abstract This paper investigates the use of genetically encoded mutation rates within a " steady state " genetic algorithm in order to provide a self-adapting mutation mechanism for incremental evolution. One of the outcomes of this work will be a reduction in the number of parameters required to be set by the operator, thus facilitating the transfer of(More)
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When, where and how is the head-tail axis of the embryo set up during development? These are such fundamental and intensely studied questions that one might expect them to have been answered long ago. Not so; we still understand very little about the cellular or molecular mechanisms that lead to the orderly arrangement of body elements along the head-tail(More)
Service-based approaches (such as Web Services and the Open Grid Services Architecture) have gained considerable attention recently for supporting distributed application development in e-business and e-science. The emergence of a service-oriented view of hardware and software resources raises the question as to how database management systems and(More)
Anne Case provided particularly helpful and insightful comments which eliminated much confusion. I thank especially Richard Wilkinson, whose work and suggestions have inspired much of this work. Although I have tried to construct a model that captures what seems to me to be the spirit of his ideas, I bear sole responsibility for the results. Helpful(More)
We present new evidence on the distribution of the ex ante risk premium based on a multi-year survey of Chief Financial Officers (CFOs) of U.S. corporations. We have responses from surveys conducted from the second quarter of 2000 through the second quarter of 2003. We find evidence that the one-year risk premium is highly variable through time, while the(More)
Distributed query processing (DQP) has been widely used in data intensive applications where data of relevance to users is stored in multiple locations. This paper argues: (i) that DQP can be important in the Grid, as a means of providing high-level, declarative languages for integrating data access and analysis; and (ii) that the Grid provides resource(More)