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[4] D. Bestle and M. Zeitz, " Canonical form observer design for nonlinear time-variable systems, " Int. [5] C. G. Broyden, " The convergence of a class of double-rank minimization algorithms, " J. Solution of output regulation of singular non-linear systems by normal output feedback, " IEEE Trans. Efficient output feedback nonlinear model predictive(More)
Cytotoxic T lymphocytes (CTL) provide protection against pathogens and tumors. In addition, experiments in mouse models have shown that CTL can also kill antigen-presenting dendritic cells (DC), reducing their ability to activate primary and secondary CD8(+) T cell responses. In contrast, the effects of CTL-mediated killing on CD4(+) T cell responses have(More)
The survival of dendritic cells (DC) in vivo determines the duration of Ag presentation and is critical in determining the strength and magnitude of the resulting T cell response. We used a mouse model to show that Ag-loaded C57BL/6 DC (MHC class II(+/+) (MHC II(+/+))) that reach the lymph node survived longer than Ag-loaded MHC II(-/-) DC, with the numbers(More)
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