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A Type IV Pilin, PilA, Contributes to Adherence of Burkholderia pseudomallei and Virulence In Vivo
ABSTRACT The Burkholderia pseudomallei K96243 genome contains multiple type IV pilin-associated loci, including one encoding a putative pilus structural protein (pilA). A pilA deletion mutant hasExpand
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N255 is a key residue for recognition by a monoclonal antibody which protects against Yersinia pestis infection.
Mab7.3 to Yersinia pestis LcrV antigen (LcrV(Ype)) protected J774A.1 macrophages in vitro from killing by a Yersinia pseudotuberculosis strain expressing LcrV(Ype). Of 4 site-directed mutations inExpand
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TNFα and IFNγ contribute to F1/LcrV-targeted immune defense in mouse models of fully virulent pneumonic plague.
Immunization with the Yersinia pestis F1 and LcrV proteins improves survival in mouse and non-human primate models of pneumonic plague. F1- and LcrV-specific antibodies contribute to protection,Expand
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Antibodies and cytokines independently protect against pneumonic plague.
Yersinia pestis causes pneumonic plague, an exceptionally virulent disease for which we lack a safe and effective vaccine. Antibodies specific for the Y. pestis F1 and LcrV proteins can protect miceExpand
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Surgical specialization and training - its relation to clinical outcome for colorectal cancer surgery.
RATIONALE, AIMS AND OBJECTIVES Surgical sub-specialization has been considered to be a major factor in improving cancer surgery-related outcomes in terms of 5-year survival and disease-freeExpand
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Direct Neutralization of Type III Effector Translocation by the Variable Region of a Monoclonal Antibody to Yersinia pestis LcrV
ABSTRACT Plague is an acute infection caused by the Gram-negative bacterium Yersinia pestis. Antibodies that are protective against plague target LcrV, an essential virulence protein and component ofExpand
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Small protective fragments of the Yersinia pestis V antigen.
Yersinia pestis is the causative agent of plague. Naturally occurring cases of the disease and the potential use of Y. pestis as a bioweapon fuel the need for efficacious vaccines. The most recentExpand
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Community mental health nursing and early intervention in dementia: developing practice through a single case history.
People Nursing in association with Journal of Clinical Nursing 13, 6b, 57-67 Community mental health nursing and early intervention in dementia: developing practice through a single case history ThisExpand
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Water balances and evapotranspiration in water- and dry-seeded rice systems
Rice is a crop that is usually grown under flooded conditions and can require large amounts of water. The objective of this 3-year study was to quantify water use in water- (WS) and dry-seeded (DS)Expand
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Underlying causes of yield spatial variability and potential for precision management in rice systems
Our current understanding of the mechanisms driving spatiotemporal yield variability in rice systems is insufficient for effective management at the sub-field scale. The overall objective of thisExpand
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