Jim Heaton

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
A number of preclinical safety pharmacology and toxicity studies have been performed on the angiostatic cortisene anecortave acetate in various species and using different routes of administration (oral, intravenous, subcutaneous, topical ocular, intraocular injection, posterior juxtascleral) and a wide range of doses (0-1,000 mg/kg). Anecortave acetate did(More)
1. Isolated perfused rabbit lungs and cultured pulmonary endothelial cells take up radiolabeled [14C]morphine in proportion to the amount of labeled drug in the medium. 2. The accumulated label is readily released from the isolated lungs by perfusion with unlabeled morphine or naloxone, but not by perfusion with Krebs-Ringer solution, sucrose or thiopental.(More)
  • 1