Additional References: 1. Lecture slides by Ravi Tiruvury 2.
BACKGROUND Fibrates are a unique hypolipidemic drugs that lower plasma triglyceride and cholesterol levels through their action as peroxisome proliferator-activated receptor alpha (PPARalpha) agonists. The activation of PPARalpha leads to a cascade of events that result in the pharmacological (hypolipidemic) and adverse (carcinogenic) effects in rodent… (More)
To investigate the causative agent of swine diarrhea, next-generation sequencing (NGS) was performed on a porcine fecal sample. The NGS reads were assembled, which generated a complete swine Deltacoronavirus genome sequence, that of strain SDCV/USA/Illinois121/2014.
Reading comprehension is largely tested in schools using handwritten responses. The paper describes computational methods of scoring such responses using handwriting recognition and automatic essay scoring technologies. The goal is to assign to each handwritten response a score which is comparable to that of a human scorer even though machine handwriting… (More)
Amidst the desolate landscape of fallen great companies, Jim Collins began to wonder: How do the mighty fall? Can decline be detected early and avoided? How far can a company fall before the path toward doom becomes inevitable and unshakable? How can companies reverse course? In How the Mighty Fall, Collins confronts these questions, offering leaders the… (More)
Handwritten essays are widely used in educational assessments, particularly in classroom instruction. This paper concerns the design of an automated system for performing the task of taking as input scanned images of handwritten student essays in reading comprehension tests and to produce as output scores for the answers which are analogous to those… (More)
The Intervention Evaluation Competition at the Work, Stress, and Health conference in Miami (March 2006) highlighted the importance of intervention evaluation studies that promote safety and health at work. A retitled, "Best Practices Evaluation Competition," has been included in the March, 2008, Work, Stress, and Health conference, in Washington, DC. This… (More)
We investigated the presence in US pigs of rotavirus H (RVH), identified in pigs in Japan and Brazil. From 204 samples collected during 2006-2009, we identified RVH in 15% of fecal samples from 10 US states, suggesting that RVH has circulated in the United States since 2002, but probably longer.
Diagnostic test sensitivity affects rate estimates for laboratory-confirmed influenza-associated hospitalizations. We used data from FluSurv-NET, a national population-based surveillance system for laboratory-confirmed influenza hospitalizations, to capture diagnostic test type by patient age and influenza season. We calculated observed rates by age group… (More)