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Using a highly selective enrichment broth, 62 isolates of vancomycin-resistant Enterococcus faecium were obtained from non-human sources; 35 isolates from raw sewage, 22 from farm animals and 5 from uncooked chickens. All strains possessed the Van A gene, conferring high-level resistance to vancomycin (MIC > or = 256 mg/L). Ribotyping of 42 of these(More)
Eight clinical isolates of vancomycin-resistant Enterococcus faecium (VRE) were obtained from four renal and four other in-patients within an 11 week period during 1992. Characterisation of the isolates by restriction enzyme analysis with Sal I and rRNA gene restriction patterns (ribotyping) showed them to be clonally related. During the next 3 months an(More)
A total of 26% of the pneumococci isolated from an outpatient clinic in Nairobi, Kenya, during 1991 to 1992 had intermediate levels of penicillin resistance. Gene fingerprinting and DNA sequencing were used to distinguish the penicillin-binding protein (PBP) 1A, 2B, and 2X genes in 23 resistant isolates. Isolates were grouped into those that had identical(More)
Pasteurella multocida is a well recognized cause of sepsis following animal contact particularly bites and scratches. Spread to prosthetic joints may occur particularly in immunocompromised patients. Immunocompromised patients with prosthetic joints should be warned that animals are potential sources of serious infection and urgent medical advice should be(More)
Two hundred and sixteen clinically significant isolates of Streptococcus pneumoniae from 138 adult patients attending clinics in Nairobi, Kenya over a 2 year period were characterized by antibiotic sensitivity testing and serotyping. Overall antibiotic resistance rates were: penicillin, 25%; tetracycline, 34%; erythromycin, 0%; chloramphenicol, 0.4%.(More)
Thirty-two isolates of clinically significant Streptococcus pneumoniae from 11 human immunodeficiency virus (HIV)-seropositive patients with single or multiple episodes of pneumonia were characterized by antibiotic susceptibility testing, serotyping, ribotyping, and repetitive extragenic palindromic polymerase chain reaction (REP-PCR). The isolates(More)
Testicular feminization syndrome, an X-linked recessive disorder in humans, is caused by the insensitivity of target organs such as testes to the stimulation of androgens. Two animal models are available, the tfm mouse and the tfm rat. In tfm rats abnormal androgen receptor binding and/or defective processing of testosterone occurs. Zinc has been reported(More)
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