Jill R Bordelon

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OBJECTIVE To identify patients with primary auditory neuropathies whose cochlear potentials to a 100 microsec click persist after click cessation and simulate synchronous auditory brain stem responses (ABRs) at high intensities. DESIGN ABRs to condensation and rarefaction clicks, as well as Maximum Length Sequence ABRs and one transtympanic(More)
Prefrontal cortical functioning depends on D1 family receptors and their complex signal transduction cascade, including protein phosphatase-1 (PP1). Three PP1 isoforms are prominent in the brain: PP1alpha, PP1beta and PP1gamma1. PP1 localization by a variety of scaffolding proteins is critical for dopamine-mediated modulation of glutamatergic(More)
Function of the olivocochlear reflex, measured by suppression of transient evoked otoacoustic emissions, is assessed in nine patients with bilateral auditory neuropathy/dys-synchrony and compared to matched control subjects with normal auditory function. TEOAEs were acquired using 65 dB peak sound pressure linear clicks with and without the presence of(More)
Mutations in DJ-1 cause autosomal recessive, early-onset Parkinson's disease (PD). The precise function and distribution of DJ-1 in the central nervous system remain unclear. In this study, we performed a comprehensive analysis of DJ-1 expression in human, monkey, and rat brains with antibodies that recognize distinct, evolutionarily conserved epitopes of(More)
Prefrontal cortical functioning depends on D1 family receptors and their complex signal transduction cascade, including protein phos-phatase-1 (PP1). Three PP1 isoforms are prominent in the brain: PP1a, PP1b and PP1g1. PP1 localization by a variety of scaffolding proteins is critical for dopamine-mediated modulation of glutamate-rgic neurotransmission. We(More)
our program received first-rate reviews and chances are we will increase our number of NIH training grant slots. Many thanks to the efforts of our faculty and students and for the innumerable hours that Yoland spent on this project during his first year as Program Director. Finally, after much deliberation and several rounds of editing, the Emory(More)
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