Jill L. Sondeen

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BACKGROUND The ability to rapidly and accurately triage, evacuate, and utilize appropriate interventions can be problematic in the early decision-making process of trauma care. With current methods of prehospital data collection and analysis, decisions are often based upon single data points. This information may be insufficient for reliable(More)
This study evaluated noninvasively determined muscle pH (pHm) and muscle oxygen saturation (SmO2) in a swine shock model that used uncontrolled hemorrhage and restricted volume resuscitation. Anesthetized 40-kg female swine underwent hemorrhage until 24 mL/kg of blood was removed (n = 26), followed by transection of the spleen, causing uncontrolled(More)
INTRODUCTION Investigation of resuscitation fluids in our swine hemorrhage model revealed moderate to severe chronic pneumonia in five swine at necropsy. Our veterinary staff suggested that we perform a retrospective analysis of prospectively collected data from these animals. We compared the data to that of ten healthy swine to determine the physiologic(More)
On the battlefield, hemorrhage from wounds remains the leading cause of mortality, accounting for 50% of all deaths [1]. Hemorrhage is also the second leading cause of mortality among injured civilians, accounting for 39% of civilian trauma deaths [2-4]. The primary field-ready methods for control of hemorrhage— tourniquets, direct pressure, bandages, and(More)
Recent clinical studies have demonstrated that high blood lactate in the prehospital setting and poor lactate clearance in the emergency department are predictive of in-hospital mortality. This analysis of data collected from a swine model of hemorrhage and restricted volume resuscitation investigated the hypotheses that noninvasive muscle pH (pHm) and H(More)
Previous studies have indicated that hemorrhage may predispose the lung to respiratory distress syndrome. Gene expression profiling with oligonucleotide microarrays was used to evaluate the genetic responses of the lung to hemorrhage. Conscious rats, chronically instrumented with a catheter and telemetry device to record blood pressure, heart rate, and(More)
Exsanguination is the major cause of death on the battlefield. Of those who die on the battlefield, it is estimated that 20% could be salvaged before exsanguination if provided with immediate care. Upon arrival at the scene, a First Responder must immediately control bleeding. If the injury is on the body surface or extremity and compressible, direct(More)
Hemorrhage is the principal cause of death of soldiers on the battlefield. With dispersed troops and future combat operations expecting longer evacuation times and limited availability of medical supplies far-forward, significant improvements in fluid resuscitation will be required if casualties are to be saved. While it is known that a drop in blood(More)
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