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Tumor necrosis factor-alpha, interleukin-1, and endotoxin stimulate the expression of vascular endothelial cell (EC) adhesion molecules. Here we describe a novel pathway of adhesion molecule induction that is independent of exogenous factors, but which is dependent on integrin signaling and cell-cell interactions. Cells plated onto gelatin, fibronectin,(More)
Several lymphocyte surface antigens are encoded by genes in the Mls region on mouse chromosome 1 [Mls, Festenstein et al. 1977; Ly-9, Ledbetter et al. 1979, Hogarth et al. 1980, Mathieson et al. 1980; Ly-17 (Ly-m20), Shen and Boyse 1980, Kimura et al. 1981; Ly-22, Tada et al. 1983]. In this report we describe a new Ly antigen (Ly-33) which is controlled by(More)
A new lymphocyte alloantigen (Ly-34) was defined by a monoclonal antibody. The antibody (IgM, K) was secreted by the hybridoma 142.331, which was obtained by the fusion of spleen cells from HRS/J mouse hyperimmunized with C 5 7 B L / 6 H 2 ~ thymocytes and SP2/0 myeloma cells. The expression of Ly-34 antigen on cells of different lymphoid organs was(More)
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