Jill E. Bower

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The Na+/K+ ATPase asymmetrically distributes sodium and potassium ions across the plasma membrane to generate and maintain the membrane potential in many cell types. Although these pumps have been hypothesized to be involved in various human neurological disorders, including seizures and neurodegeneration, direct genetic evidence has been lacking. Here, we(More)
Model organisms such as Drosophila are receiving increased attention for studies of human neurodegenerative disease. Although the merit of such systems for genetic studies is apparent, the relevance of a neurodegenerative phenotype in flies, whose lifespan is measured in weeks, to the long duration of human neurodegenerative diseases would seem less clear.(More)
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