Jilin Sun

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phosphorylated tyrosine residues at the cytoplasmic tails 2 Corresponding author of the receptors (Schlessinger and Ullrich, 1992). Although several signal transduction pathways downstream from Heparin-binding epidermal growth factor-like growth RTKs have been elucidated, it is still not completely factor (HB-EGF) is a potent mitogen and chemotactic(More)
BACKGROUND Therapeutic antibodies targeting the IGF1R have shown diverse efficacy and safety signals in oncology clinical trials. The success of these agents as future human therapeutics depends on understanding the specific mechanisms by which these antibodies target IGF1R signaling. METHODOLOGY/PRINCIPAL FINDINGS A panel of well-characterized assays was(More)
An analysis of cyclone activity in winter associated with years of strong and weak Aleutian Low in the North Pacific is presented. From 1958-2004, ten winters with a strong Aleutian Low are defined as the strong years, while eight winters with a weak Aleutian Low are defined as the weak years. Employing a system-centered Lagrangian method, some(More)
OBJECTIVE To localize the language cortex associated with Chinese word processing by magnetic source imaging (MSI). METHODS Eight right-handed and one left-handed healthy native Chinese subjects were examined by magnetoencephalography (MEG) and a 1.5T magnetic resonance imaging (MRI) unit. All subjects were given pure tone stimuli 50 times, 150 pairs of(More)
OBJECTIVE To investigate the relationship between cognitive impairment and somatosensory evoked magnetic field and auditory evoked magnetic field changes in elderly male patients with subcortical ischemic vascular dementia (SIVD). METHODS Magnetoencephalography (MEG) was used to record evoked magnetic field changes from 4 SIVD patients (76-88 years), 3(More)
Auditory evoked magnetic fields were recorded from 15 patients with acute cerebral infarction and 11 healthy volunteers using magnetoencephalography. The auditory stimuli of 2 kHz pure tone were binaurally presented with an interstimulus interval of 1 second. The intensity of stimuli was 90 dB and the stimulus duration was 8 ms. The results showed that the(More)
OBJECTIVE To access the pathological changes of the functional localization of the primary auditory cortex in auditory neuropathy patients using magnetoencephalography (MEG). METHODS The M100 waves of cortical evoked magnetic fields (AEF) evoked by 0.5, 1, 2, 4, 6, 8 kHz pure tones were measured respectively in 10 auditory neuropathy patients (20 ears)(More)
OBJECTIVE To evaluate the value of magnetic source imaging (MSI) in the functional localization of the primary auditory cortex. METHODS The M100 waves of cortical auditory evoked magnetic fields (AEFs) evoked by 0.5, 1, 2, 4 and 8 kHz pure tones in 5 subjects and by 2 kHz pure tones in 25 healthy young subjects were measured respectively (16 males and 14(More)