Jijrg Niggemann

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Ventricular cardiomyocytes isolated from adult rat heart were used to analyze the effect of insulin on the phosphorylation of DNA-binding nuclear proteins and to elucidate the potential involvement of protein phosphatase-1 (PP-1) and PP-2A in this hormonal action. Cells were labelled with [33P]orthophosphate, stimulated with insulin (1.7 x 10(-7) M) and(More)
Ventricular cardiomyocytes isolated from adult rat heart were used to analyze the effect of insulin on the phosphorylation of DNA-binding nuclear proteins and to elucidate the potential involvement of protein phosphatase-1 (PP-1) and PP-2A in this hormonal action. Cells were labelled with [33P]orthophosphate, stimulated with insulin (1.7 x lo-’ M) and(More)
A chemoenzymatic approach is described towards the branched tetrasaccharide repeating unit, beta-D-Galp- (1-->4)-beta-D-Glcp-(1-->6)-[beta-D-Galp-(1-->4)]-beta-D-GlcpNac, of Streptococcus pneumoniae type 14 in a form suitable for conjugation. The linear trisaccharide acceptor, beta-D-Galp-(1-->4)-beta-D-Glcp-(1-->6)-beta-D-GlcpNAc-(1-->O)CH2CH++ + = CH2,(More)
Diagnosis and post-therapeutic follow-up of tumour patients necessitates morphological and particularly functional imaging methods. For the latter approach positron emission tomography has proven a valid tool for the measurement of perfusion, of energy consumption parameters such as oxygen extraction, glucose metabolism and amino acid uptake. However,(More)
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