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Prior intracellular recording and labeling experiments have documented local-circuit and projection neurons in the spinal trigeminal (V) nucleus with axons that arborize in more rostral and caudal spinal trigeminal subnuclei and nucleus principalis. Anterograde tracing studies were therefore carried out to assess the origin, extent, distribution, and(More)
Immunocytochemistry with an antiserum directed against serotonin (5-HT) was used to assess the development of the representation of the body surface in the rat's primary somatosensory cortex (S-I). Within 1 hour of birth (P-O), 5-HT-positive fibers were present in the marginal zone, the cortical plate, and developing layers V and VI. Immunoreactivity in the(More)
We have previously reported that neonatal (P3) serotonin (5-HT) depletion results in a significant decrease in the number of dendritic spines per 50 microns of dendritic length on dentate granule cells. This effect is specific and permanent. Neither total dendritic length nor the number of dendritic segments is affected by 5-HT depletion. The area dentata(More)
OFDM is a promising technique being used for bandwidth efficient communication over the power-line channel. It provides excellent possibilities to adapt to the frequency-selectivity of the channel. The influence of impulsive noise on the OFDM transmission is not well analyzed yet. We choose Middletons Class A man-made noise model to statistically describe(More)
The response of astrocytes to pharmacological alterations of the serotonin (5-HT) content of the dorsal area dentata was studied by immunocytochemistry for S100 beta. Stereological analysis revealed changes in the density of astrocytic elements in conditions of 5-HT depletion and elevated 5-HT levels. There was a direct relationship between the expression(More)
The appearance of serotonergic (5-HT) neurons and projections early in central nervous system (CNS) development has resulted in the hypothesis that 5-HT is an important factor in neuronal differentiation and synaptogenesis. Studies of the effects of 5-HT on the development of molluscan and mammalian neurons in vitro support this hypothesis, but mammalian in(More)
Neurons of the nucleus basalis magnocellularis (NBm) of the rat are contained within the ventromedial globus pallidus and adjacent internal capsule. Horseradish peroxidase injection limited to the ventromedial globus pallidus result in sparse neuronal labeling in a variety of brainstem, thalamic and hypothalamic nuclei, and the basal nuclei identified after(More)
Neonatal serotonin (5-HT) depletion or 5-HT1a receptor blockade results in a significant and permanent reduction in the number of dentate granule cell dendritic spines. The purpose of this study was to determine whether the loss of spines was accompanied by a reduction in molecular layer synaptic profile density. Rat pups were treated with(More)
The present study sought to verify effects of 5-HT on synaptic density at the ultrastructural level, to determine whether the 5-HT1a receptor is important for the maintenance of synaptic connections and to obtain evidence implicating S100 beta in the apparent neurotrophic actions of 5-HT. Reduction of hippocampal 5-HT with para-chloroamphetamine (PCA)(More)