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Existing thermal management systems for microprocessors assume that the thermal resistance of the heat-sink is constant and that the objective of the cooling system is simply to avoid thermal emergencies. But in fact the thermal resistance of the usual forced-convection heat-sink is inversely proportional to the fan speed, and a more rational objective is(More)
BACKGROUND Previous differential coexpression analyses focused on identification of differentially coexpressed gene pairs, revealing many insightful biological hypotheses. However, this method could not detect coexpression relationships between pairs of gene sets. Considering the success of many set-wise analysis methods for microarray data, a coexpression(More)
SUMMARY ArrayXPath (http://www.snubi.org/software/ArrayXPath/) is a web-based service for mapping and visualizing microarray gene-expression data with integrated biological pathway resources using Scalable Vector Graphics (SVG). Deciphering the crosstalk among pathways and integrating biomedical ontologies and knowledge bases may help biological(More)
Cloud infrastructure providers deploy Dynamic Resource Management (DRM) to minimize the cost of datacenter operation, while maintaining the Service Level Agreement (SLA). Such DRM schemes depend on the capability to migrate virtual machine (VM) images. However, existing migration techniques are not suitable for highly utilized clouds due to their latency(More)
MOTIVATION In determining the function of a gene, it provides much information to observe the changes in a biological system after disruption of the gene of interest through its knockout. Thanks to the microarray technology, it is now possible to profile transcriptional changes of the whole genome, thus differentiating genes that are significantly affected(More)
Running title: Integrating microarray data with biomedical ontology and pathway 2 ABSTRACT Summary: ArrayXPath (http://www.snubi.org/software/ArrayXPath/) is a web-based service for mapping and visualizing microarray gene-expression data with integrated biological pathway resources using Scalable Vector Graphics (SVG). Deciphering the crosstalk among(More)
BACKGROUND The Gene Ontology (GO) provides a controlled vocabulary for describing genes and gene products. In spite of the undoubted importance of GO, several drawbacks associated with GO and GO-based annotations have been introduced. We identified three types of semantic inconsistencies in GO-based annotations; semantically redundant, biological-domain(More)
MOTIVATION A challenge in microarray data analysis is to interpret observed changes in terms of biological properties and relationships. One powerful approach is to make associations of gene expression clusters with biomedical ontologies and/or biological pathways. However, this approach evaluates only one cluster at a time, returning long unordered lists(More)
—Recent efforts towards mobile cloud propose to offload mobile applications to cloud servers for the improved performance and battery life of mobile devices. However, existing schemes completely ignore the costs of cloud resources by assuming that idle servers are always available for free of charge. These unrealistic assumptions make each server run only a(More)
BACKGROUND/AIMS To examine the correlation between radiological joint damage and serological parameters in early rheumatoid arthritis (RA). METHODS This retrospective study reviewed the records of 216 patients diagnosed with RA and classified them according to disease duration: group 1, </= 24 months; group 2, > 24 months; and group 3, all patients(More)