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The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture
ABSTRACT Atherosclerosis is the main pathophysiological process underlying coronary artery disease (CAD). Acute complications of atherosclerosis, such as myocardial infarction, are caused by theExpand
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The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction.
Smokers have an elevated risk of cardiovascular disease but the origin(s) of this increased risk are incompletely defined. Considerable evidence supports an accumulation of the oxidant-generatingExpand
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Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation
Singlet molecular oxygen (1O2) has well-established roles in photosynthetic plants, bacteria and fungi1–3, but not in mammals. Chemically generated 1O2 oxidizes the amino acid tryptophan toExpand
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