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Nowadays, Floating Car Data (FCD), which is becoming an important way to acquire traffic information, has been widely taken to estimate speed or travel time on road. In this paper, we introduce the concept of outlier mining into Automatic Incident Detection (AID) based on FCD and propose a novel AID approach on urban arterial road. According to the(More)
Acute administration of opioids produces analgesia, while chronic administration induces tolerance and dependence. Aquaporin 4 (AQP4) is most strongly expressed in astrocytes throughout central nervous system, and plays an important role in some pathophysiological processes in brain. However, whether AQP4 modulates opioid analgesia, tolerance and dependence(More)
Our previous study indicated that aquaporin4 (AQP4) deficiency potentiated morphine analgesia, but attenuated tolerance and physical dependence induced by chronic exposure to morphine. However, the mechanisms remained to be explored. In the present study, effects of AQP4 deficiency on opioid receptor characteristics were investigated by [(3)H]-diprenorphine(More)
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