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The effect of absorption rate on the pharmacokinetics of ibuprofen enantiomers was investigated in 12 healthy Han Chinese male volunteers following oral administration of immediate-release (IR) and sustained-release (SR) preparations containing racemic ibuprofen (rac-ibuprofen). The area under the curve of the plasma concentration-time curve (AUC;(More)
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To truly make automation economical, there needs to be a shift in robotic performance: from highly specific at one task to general-purpose across many tasks. Unfortunately, such additional functionality is not cost-effective without a sacrifice in performance. In the case of robotics, it is a sacrifice in accuracy. This paper first investigates an industry(More)
This paper illustrates the design and implementation of a robotic software system based on robot-human interactions, which increases the applications of low-cost, inaccurate robots such as Baxter. The first four parts of the paper discuss the motivation, market & industry, IP strategy and system workflow. Then the paper explains a specific technical(More)
This project concerns the development of a system which allows tasks to be taught to a robotic manipulator using learning by demonstration. A subsystem calculates the accuracy required of the manipulator and determines which portion of the learned task it is able to perform. Therefore, the system can avoid performing tasks that require accuracy beyond the(More)
While humans can naturally feel forces as they manipulate objects, robots need special instrumentation to provide this capability. Force and torque sensing is crucial to enable robots to perform manipulation tasks such as picking up delicate items, screwing in parts for assembly, and handling deformable objects. In this paper, I present a force sensing data(More)
We previously reported that autocrine TNF-α (TNF) is responsible for JNK pathway activation in a subset of acute myeloid leukemia (AML) patient samples, providing a survival/proliferation signaling parallel to NF-κB in AML stem cells (LSCs). In this study, we report that most TNF-expressing AML cells (LCs) also express another pro-inflammatory cytokine,(More)
The phosphorylated form of Pten (p-Pten) is highly expressed in >70% of acute myeloid leukemia samples. However, the role of p-Pten in normal and abnormal hematopoiesis has not been studied. We found that Pten protein levels are comparable among long-term (LT) hematopoietic stem cells (HSCs), short-term (ST) HSCs, and multipotent progenitors (MPPs);(More)
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