Jiefeng Weng

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Experimental and clinical evidence show that liver fibrosis is potentially reversible. Hepatic stellate cells (HSCs) play a key role in the development of liver fibrosis. Some studies have shown that reversine could induce cell apoptosis. We attempted to elucidate the effect of reversine on cell cycle, apoptosis, and activation of HSCs. Data showed that(More)
The aim of the present study was to investigate the inhibitory effects of thalidomide in the hepatocellular carcinoma nude mouse model in order to provide new insights into a comprehensive clinical intervention for hepatocellular carcinoma. MHCC97 cells were routinely cultured, passaged and adjusted to a single cell suspension with a concentration of(More)
BACKGROUND/AIMS Hepatic metastases from the colorectal carcinoma frequently recur after resection and microscopic residual cancer lesions (RCL) could be important in the development of recurrence. The aim of our study was to investigate an existence of microscopic RCL after modern chemotherapy and its correlation with the preoperative CT imaging. (More)
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