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The understanding of molecular mechanism underlying ischemia/reperfusion-induced neuronal death and neurological dysfunction may provide therapeutic targets for ischemic stroke. The up-regulated miRNA-30a among our previous identified 19 MicroRNAs (miRNAs) in mouse brain after 6 h middle cerebral artery occlusion (MCAO) could negatively regulate Beclin 1(More)
Understanding the molecular mechanism of cerebral hypoxic preconditioning (HPC)-induced endogenous neuroprotection may provide potential therapeutic targets for ischemic stroke. By using bioinformatics analysis, we found that miR-181b, one of 19 differentially expressed miRNAs, may target aconitate hydratase (ACO2), heat shock protein A5 (HSPA5), and(More)
Text classification is widely used in many realworld applications. To obtain satisfied classification performance, most traditional data mining methods require lots of labeled data, which can be costly in terms of both time and human efforts. In reality, there are plenty of such resources in English since it has the largest population in the Internet world,(More)
To date, there have been massive Semi-Structured Documents (SSDs) during the evolution of the Internet. These SSDs contain both unstructured features (e.g., plain text) and metadata (e.g., tags). Most previous works focused on modeling the unstructured text, and recently, some other methods have been proposed to model the unstructured text with specific(More)
Micro-RNAs (miRs) have emerged as key gene regulators in many diseases, including stroke. We recently reported that miR-30a protects N2A cells against ischemic injury, in part through enhancing beclin 1-mediated autophagy. The present study explores further the involvement of miR-30a in ischemia-induced apoptosis and its possible mechanisms in primary(More)
OBJECTIVES To investigate the health effects of 1-bromopropane (1-BP) and its dose-dependency in 1-BP production factories in China. METHODS Data of 60 female and 26 male workers in three 1-BP factories and the same number of age-, sex-, and region-matched controls were interviewed and examined. The time-weighed average exposure levels of individual(More)
The ability to search literature and collect/aggregate metrics around publications is a central tool for modern research. Both academic and industry researchers across hundreds of scientific disciplines, from astronomy to zoology, increasingly rely on search to understand what has been published and by whom. Microsoft Academic Search is an open platform,(More)
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