Jie-ying Peng

  • Citations Per Year
Learn More
Oral submucous fibrosis (OSF) is a chronic inflammatory disease characterized by the accumulation of excess collagen, and areca nut chewing has been proposed as a significant etiological factor for disease manifestation. However, the underlying molecular mechanisms regarding areca nut chewing-induced OSF are only partially understood. Herein, we reported(More)
Betel nut chewing is the most common cause of oral submucous fibrosis (OSF). Arecoline is the main component of the betel nut, and is associated with the occurrence and development of OSF through cytotoxicity, genotoxicity and DNA damage. Similar types of stimuli elicit differential responses in different cells. In the present study, we investigated the(More)
OBJECTIVE To apply the bioinformatics tools for analyzing the differentially expressed genes in oral submucous fibrosis (OSF) to obtain the implied biological significance. METHODS By using DAVID and Onto-express bioinformatic tools, 865 differentially expressed genes in OSF were analyzed and the analysis of chromosome location, gene ontology (GO) and(More)
OBJECTIVE To explore the effect of astragalus polysaccharides-chitosan/polylactic acid (AP-C/PLA) scaffolds and bone marrow stem cells (BMSCs) on periodontal regeneration of experimentally horizontal periodontal defects in dogs. METHODS Dog BMSCs were isolated from the bone marrow and then cultured in a conditioned medium to be induced for osteogenesis.(More)
OBJECTIVE To observe the growth and osteogenic property of cultured dog bone marrow stem cells (BMSCs) by investigating the effects of astragalus polysaccharides (APS) on the proliferation and ultrastructure of BMSCs into osteoblasts in vitro. METHODS BMSCs osteogenic property was detected by improved Wright-Giemsa, Gomori and alizarin dyeing method. The(More)
OBJECTIVE To explore the protective effect of allicin on nicotine-induced oxidative damage to human periodontal ligament cells (HPDLCs). METHODS (1) Establish nicotine-induced oxidative damage model on HPDLCs. Use water-soluble tetrazolium (WST) colorimetric method to find out the nicotine concentration (X) that could inhibit HPDLCs' growth for the(More)
OBJECTIVE To investigate the relationship between tooth abrasion and long-term chewing betel nut. METHODS The time, frequency, clinical features of occlusal abrasion, and results of pantomography were studied in 64 patients with the habits of chewing betel nut. RESULTS The occlusal surfaces of all patients had abrasion from mild to severe. The longer(More)
OBJECTIVE To observe the biological behavior of canine bone marrow stromal cells (BMSCs) cultured in vitro with the astragalus polysaccharides-chitosan/polylactic acid (AP-C/PLA) and with the chitosan/polylactic acid (C/PLA) and to find a suitable compound material for periodontal tissue engineering. METHODS BMSCs (induced 14 days by 50 mg/L vitamine C,(More)
  • 1