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  • X L Du, Diane Edelstein, +5 authors Michael A. Brownlee
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2000 (First Publication: 24 October 2000)
  • The hexosamine pathway has been implicated in the pathogenesis of diabetic complications. We determined first that hyperglycemia induced a decrease in glyceraldehyde-3-phosphate dehydrogenaseContinue Reading
  • Robert Yu, Weiwei Lei, +4 authors Ah Ng Tony Kong
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 1999 (First Publication: 24 September 1999)
  • Mitogen-activated protein kinase (MAPK) cascades are activated by diverse extracellular signals and participate in the regulation of an array of cellular programs. In this study, we investigated theContinue Reading