Ranran Liu12
Maiqing Zheng10
12Ranran Liu
10Maiqing Zheng
9Bin Lu
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Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past few years, but our understanding of the genetic basis of T2D in ethnically diverse populations remains limited. We performed a genome-wide association study and a replication study in Chinese Hans comprising 8,569 T2D case subjects and 8,923 control subjects(More)
—Cyber-Individual, with a short term 'Cyber-I', is a real individual's counterpart in cyberspace. It is closely related to human-centric computing ideology which focuses on placing human in the center of computing. The study on Cyber-I tries to reexamine and analyze human essence in the digital era. Cyber-I's vision is to create a unique, digital,(More)
OBJECTIVE We aimed to investigate whether elevated serum uric acid concentrations are associated with higher risk of metabolic syndrome (MetS) and carotid atherosclerosis in patients with type 2 diabetes. METHODS We conducted a population-based cross-sectional survey in Shanghai, with a total of 395 men and 631 women age 41 to 92 years. The carotid artery(More)
BACKGROUND Recent genome-wide association studies (GWASs) have reported several genetic variants to be reproducibly associated with type 2 diabetes. Additional variants have also been detected from a metaanalysis of three GWASs, performed in populations of European ancestry. In the present study, we evaluated the influence of 17 genetic variants from 15(More)
  • Huan-Xian Cui, Ran-Ran Liu, Gui-Ping Zhao, Mai-Qing Zheng, Ji-Lan Chen, Jie Wen
  • 2011
Intramuscular fat (IMF) is one of the important factors influencing meat quality, however, for chickens, the molecular regulatory mechanisms underlying this trait have not yet been determined. In this study, a systematic identification of candidate genes and new pathways related to IMF deposition in chicken breast tissue has been made using gene expression(More)
Meat quality is an important economic trait in chickens. To identify loci and genes associated with meat quality traits, we conducted a genome-wide association study (GWAS) of F2 populations derived from a local Chinese breed (Beijing-You chickens) and a commercial fast-growing broiler line (Cobb-Vantress). In the present study, 33 association signals were(More)
BACKGROUND Excessive production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. Previous studies have indicated that activation of protein kinase C (PKC) can lead to iNOS induction. Because of the existence of(More)