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Increased nitroxidative stress causes mitochondrial dysfunctions through oxidative modifications of mitochondrial DNA, lipids, and proteins. Persistent mitochondrial dysfunction sensitizes the target cells/organs to other pathological risk factors and thus ultimately contributes to the development of more severe disease states in alcoholic and nonalcoholic(More)
Ambient Assisted Living (AAL) is of particular relevance to those who may suffer from Alzheimer's Disease or dementia, and, of course, their carers. The slow but progressive nature of the disease, together with its neurological nature, ultimately compromises the behavior and function of people who may be essentially healthy from a physical perspective. An(More)
Activity recognition is fundamental to many of the services envisaged in pervasive computing and ambient intelligence scenarios. However, delivering sufficiently robust activity recognition systems that could be deployed with confidence in an arbitrary real-world setting remains an outstanding challenge. Developments in wireless, inexpensive and unobtrusive(More)
We previously reported that acetaminophen (APAP, 4-hydroxyacetanilide) caused apoptosis of C6 glioma cells. Therefore, we hypothesized that the level of p53, which usually stimulates apoptosis, might be increased after APAP exposure. However, APAP exposure for 24 h markedly decreased the p53 content and its downstream target p21 in a concentration-dependent(More)
– Midwest ISO's real-time market design with energy and ancillary service co-optimization is reported in this paper. The key components of Midwest ISO's real-time market are described including intra-day reliability commitment, transmission security management, real-time dispatch and pricing. The RT SCED formulation at the core of the real-time dispatch and(More)