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The Cloud computing emerges as a new computing paradigm which aims to provide reliable, customized and QoS guaranteed dynamic computing environments for end-users. In this paper, we study the Cloud computing paradigm from various aspects, such as definitions, distinct features, and enabling technologies. This paper brings an introductional review on the(More)
Cloud computing emerges as a new computing paradigm which aims to provide reliable, customized and QoS guaranteed computing dynamic environments for end-users. This paper reviews recent advances of Cloud computing, identifies the concepts and characters of scientific Clouds, and finally presents an example of scientific Cloud for data centers
A poor cache behavior can significantly prohibit achieving high speedup and scalability of parallel applications. This means optimizing a program with respect to cache locality can potentially introduce considerable performance gain. As a consequence, programmers usually perform cache locality optimization for acquiring the expected performance of their(More)
Microprocessor architecture for both commercial and academical purpose is coming into a new generation: multiprocessors on a chip. Together with this novel architecture, questions and research topics also arise. For example, how to design the on-chip caches to avoid memory operations becoming the performance bottleneck? In this work, we study the impact of(More)
Cyberinfrastructure offers a vision of advanced knowledge infrastructure for research and education. It integrates diverse resources across geographically distributed resources and human communities. Cy-beraide is a service oriented architecture and abstraction framework that integrates a large number of available commodity libraries and allows users to(More)
Vascular smooth muscle cell (VSMC) apoptosis accelerates atherosclerosis and promotes restenosis following vascular injury. The current study examined the effects of cellular repressor of E1A-stimulated genes (CREG), a novel glycoprotein inhibiting transcription activation, on the regulation of VSMC apoptosis. Serum starvation or treatment of human VSMCs(More)
Cattle are the natural hosts of bovine viral diarrhea virus (BVDV), which causes mucosal disease, respiratory and gastrointestinal tract infections, and reproductive problems in cattle. However, BVDV can also infect goats, sheep, deer, and pigs. The prevalence of BVDV infection in pig herds has substantially increased in the last several years, causing(More)
Phenotypic modulation of vascular smooth muscle cells (VSMCs) plays a critical role in the pathogenesis of a variety of proliferative vascular diseases. The cellular repressor of E1A-stimulated genes (CREG) has been shown to play an important role in phenotypic modulation of VSMCs. However, the mechanism regulating CREG upstream signaling remains unclear.(More)
Bone marrow-derived mesenchymal stem cells (MSCs) have great potential for repair after myocardial infarction. However, poor viability of transplanted MSCs in the ischemic heart has limited their therapeutic potential. Cellular repressor of E1A-stimulated genes (CREG) has been identified as a potent inhibitor of apoptosis. The aim of this study was to(More)