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BACKGROUND Control genes, which are often referred to as housekeeping genes, are frequently used to normalise mRNA levels between different samples. However, the expression level of these genes may vary among tissues or cells and may change under certain circumstances. Thus, the selection of housekeeping genes is critical for gene expression studies. To(More)
Gamma-aminobutyric acid (GABA) transporter subtype 1 (GAT1), which transports extracellular GABA into presynaptic neurons, plays an important regulatory role in the function of GABAergic systems. However, the contributions of the GAT1 in regulating mental status are not fully understood. In this paper, we observed the behavioral alterations of GAT1 knockout(More)
For resource-limited language pairs, coverage of the test set by the parallel corpus is an important factor that affects translation quality in two respects: 1) out of vocabulary words; 2) the same information in an input sentence can be expressed in different ways, while current phrase-based SMT systems cannot automatically select an alternative way to(More)
Cx50 (connexin50), a member of the α-family of gap junction proteins expressed in the lens of the eye, has been shown to be essential for normal lens development. In the present study, we identified a CaMBD [CaM (calmodulin)-binding domain] (residues 141-166) in the intracellular loop of Cx50. Elevations in intracellular Ca2+ concentration effected a 95%(More)
Crosstalk between the oestrogen receptor (ER) and ERBB2/HER-2 pathways has long been implicated in breast cancer aetiology and drug response, yet no direct connection at a transcriptional level has been shown. Here we show that oestrogen-ER and tamoxifen-ER complexes directly repress ERBB2 transcription by means of a cis-regulatory element within the ERBB2(More)
We have studied the exciton properties of single-wall carbon nanotubes by solving the Bethe-Salpeter equation within tight-binding models. The screening effect of the ␲ electrons in carbon nanotubes is treated within the random phase and static screened approximations. The exciton wave functions along the tube axis and circumference are discussed as a(More)
Although systematic measurements of the Sun's polar magnetic field exist only from mid-1970s, other proxies can be used to infer the polar field at earlier times. The observational data indicate a strong correlation between the polar field at a sunspot minimum and the strength of the next cycle, although the strength of the cycle is not correlated well with(More)
In energy constrained wireless sensor networks, node scheduling is an effective approach to improving the energy efficiency and prolonging the network lifetime. In this paper, we propose a distributed, lightweight, and location-unaware scheduling scheme for randomly deployed wireless sensor networks. The basic idea of the scheduling scheme is to organize(More)