Jiayuan Wang

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FoxD3 is a transcription factor of the forkhead gene family. We investigated its expression in invasive ductal carcinomas (IDC) of the breast and its association with metastasis. The expression of FoxD3, human epidermal growth factor receptor-2 (HER-2), estrogen receptor (ER), progesterone receptor (PR) and Ki67 was examined by immunohistochemistry in(More)
The Talbot effect of the surface plasmon polaritons (SPPs) using SPP launching gratings is studied experimentally. Talbot carpets are obtained and the Talbot distance is given when the paraxial approximation is not satisfied. Multi-layer and multi-level-phase launching gratings are designed to enhance the intensities of the amplitude-modulated revivals.(More)
Sulfate aerosols exert profound impacts on human and ecosystem health, weather, and climate, but their formation mechanism remains uncertain. Atmospheric models consistently underpredict sulfate levels under diverse environmental conditions. From atmospheric measurements in two Chinese megacities and complementary laboratory experiments, we show that the(More)
Based on a novel phase-sieve method by in-plane interference processes, a well-designed nonperiodic nanogroove array on gold surface is proposed as a multifunctional and multi-output plasmonic meta-element (MPM) for surface plasmon polariton waves. An MPM functions as a plasmonic lens (PL) as well as a plasmonic array illuminator (PAI), and another MPM acts(More)
A compact polarization rotator (PR) for silicon-based slot waveguides is proposed, where the slot region including the upper claddings is filled with liquid crystals (LCs). With the anisotropic features of the LCs, the transverse field components of eigenmodes have almost identical amplitudes, leading to a high modal hybridness. As a result, the TE (TM)(More)
The anti-HER2 monoclonal antibody trastuzumab is central to the treatment of HER2-positive gastric cancer (GC); however, its responses are limited. HER3 seems to be the preferred dimerization partner with HER2 and is emerging as a key target for complete blockade of downstream pathways and better clinical response. In this study, we report that novel(More)
Cell cycle dysregulation is common in human malignancies, and CDK4/6 inhibitors targeting cell cycle have potential antitumor activity. SHR6390 is a novel small molecule inhibitor specifically targeting the CDK4/6 pathway. However, the role of SHR6390 in esophageal squamous cell carcinoma (ESCC) remains unknown, which will be investigated in our study. Eca(More)
Colorectal cancer (CRC) is one of the most lethal cancers worldwide. Mutations in KRAS occur with the frequency of 30-50% in CRC leading to decreased therapeutic response to anti-epidermal growth factor receptor (EGFR) agents. Recently GATA2 was proven to be essential in the survival of KRAS mutant non-small cell lung cancer (NSCLC) cells. However, the(More)
We present the design of a plasmonic lens (PL) which is composed of pixelated nano-grooves on a gold film for the coupling and focusing of surface plasmon polaritons (SPPs) into multiple focal spots on the optical axis. The pixelated grooves are arranged along the y-axis and the x-position of each groove is optimized by the simulated annealing algorithm.(More)