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According to the very limited cancer registry, incidence and mortality rates for female breast cancer in China are regarded to be increasing especially in the metropolitan areas. Representative data on the breast cancer profile of Chinese women and its time trend over years are relatively rare. The aims of the current study are to illustrate the breast(More)
Analyses of mitochondrial (mt) genome sequences in recent years challenge the current working hypothesis of Nematoda phylogeny proposed from morphology, ecology and nuclear small subunit rRNA gene sequences, and raise the need to sequence additional mt genomes for a broad range of nematode lineages. We sequenced the complete mt genomes of three Ascaridia(More)
BACKGROUND The prevalence of BRCA1/2 variants in Chinese breast cancer patients varies among studies. Germline or somatic BRCA1/2 mutations are associated with sensitivity to poly(ADP-ribose) polymerase-1 inhibitors and DNA-damaging agents. We aimed to investigate the distribution of both somatic and germline BRCA1/2 variants in unselected Chinese breast(More)
OBJECTIVE To study the potential effect of gene-environment interaction between CYP1A1 and serum dichlorodiphenyldichloroethane (DDT) levels on the risk of breast cancer in women, in China. METHODS A case-control study was conducted. From Dec. 2003 to Sep. 2004, 104 women with histologically confirmed breast cancers and 154 noncancerous controls from a(More)
BACKGROUND The characteristics of established risk factors for breast cancer may vary among countries. A better understanding of local characteristics of risk factors may help in devising effective prevention strategies for breast cancer. METHODS Information on exposures to risk factors was collected from the medical charts of 4211 women with breast(More)
CYP1A1, CYP1B1, and COMT are key enzymes involved in estrogen metabolism. Soy isoflavones, phytoestrogens found in soy foods, may modify the activity of these enzymes. A case-control study was conducted to assess the associations between soy isoflavone intake and the CYP1A1 Ile462Val, CYP1B1 Val432Leu, and COMT Val158Met polymorphisms and breast cancer, as(More)
Natural NQO1 [NAD(P)H quinine oxidoreductase 1] inducing agents play a critical role in cancer chemoprevention. The expression of NQO1 is regulated by Michael reaction acceptors (MRAs) via the Keap1/Nrf2/ARE signaling pathway. The aims of this study were to identify and characterize novel effective chemopreventive agents from naturally occurring products.(More)
Scan matching, an approach to recover the relative position and orientation of two laser scans, is a very important technique for indoor positioning and indoor modeling. The iterative closest point (ICP) algorithm and its variants are the most well-known techniques for such a problem. However, ICP algorithms rely highly on the initial guess of the relative(More)
BACKGROUND AND OBJECTIVE Incidence of and mortality rates for breast cancer continue to rise in the People's Republic of China. The purpose of this study was to analyze differences in characteristics of breast malignancies between China and the U.S. METHODS Data from 384,262 breast cancer patients registered in the U.S. Surveillance, Epidemiology, and End(More)
A survey was performed to know blood lead level (BLL) of children under seven and the risk factors of high BLL in Chengdu, China in 2004. The mean BLL in children under seven in Chengdu was 63.88 microg/L. The detection rate of high BLL was 8.21%. Chengdu is a moderate popular region of lead poisoning. Substitute of breast milk, living at the base floor or(More)