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Axonal degeneration is a hallmark of many neuropathies, neurodegenerative diseases, and injuries. Here, using a Drosophila injury model, we have identified a highly conserved E3 ubiquitin ligase, Highwire (Hiw), as an important regulator of axonal and synaptic degeneration. Mutations in hiw strongly inhibit Wallerian degeneration in multiple neuron types(More)
Falls are the leading cause of injury and death among older adults in the US. Computer vision systems offer a promising way of detecting falls. The present paper examines a fall detection and reporting system using the Microsoft Kinect sensor. Two algorithms for detecting falls are introduced. The first uses only a single frame to determine if a fall has(More)
Live imaging is an important technique for studying cell biological processes, however this can be challenging in live animals. The translucent cuticle of the Drosophila larva makes it an attractive model organism for live imaging studies. However, an important challenge for live imaging techniques is to noninvasively immobilize and position an animal on(More)
For the increasing attention focused on saving endangered environments, there is a growing need for developing membrane materials able to perform complex functions such as removing radioactive pollutants and oil spills from water. A major challenge is the scalable fabrication of membranes with good mechanical and thermal stability, superior resistance to(More)
In this work, we demonstrated a viable experimental scheme for in-situ probing the effects of Au nanoparticles (NPs) incorporation on plasmonic energy transfer in Cu(In, Ga)Se2 (CIGS) solar cells by elaborately analyzing the lifetimes and zero moment for hot carrier relaxation with ultrabroadband femtosecond pump-probe spectroscopy. The signals of enhanced(More)
It is not uncommon for negotiating agents to involve complex utility functions in the negotiation process. To search for an optimised solution in a large and complex space can be very time consuming. The choice of appropriate parameter settings for searching methods can have significant impact on the negotiation result. In this paper, we report a series of(More)
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