Jiaxin Zhao

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C-X-C chemokine receptor 4 (CXCR4) is frequently over-expressed in various types of cancer; many agents against CXCR4 are in clinical development currently despite variable data for the prognostic impact of CXCR4 expression. Here eighty-five studies with a total of 11,032 subjects were included to explore the association between CXCR4 and progression-free(More)
Human fetal neural stem cells (hNSCs) are used to treat a variety of neurological disorders involving spinal cord injury (SCI). Although their mechanism of action has been attributed to cell substitution, we examined the possibility that NSCs may have neuroprotective activities. The present article studied the action of hNSCs on protecting neurons and(More)
An idealized model consisting of a thermal conductor and a thermal insulator separated by a thin layer of lubricating fluid is developed to investigate thermoelastic instability with fluid lubrication. The governing equations are solved for the critical speed. A new dimensionless parameter H 0 is defined to predict the critical speed. Furthermore, the(More)
This paper deals with the effects of friction material properties on thermoelastic instability (TEI) and the associated dominant deformation mode. Both analytical and finite element models are constructed for determining the variation of the critical speed and the dominant TEI mode. Some important factors, e.g. the nonconductive friction material as well as(More)
Glioblastoma (GBM) is the most common and most aggressive central nervous system tumor in adults. Due to GBM cell invasiveness and resistance to chemotherapy, current medical interventions are not satisfactory, and the prognosis for GBM is poor. It is necessary to investigate the underlying mechanism of GBM metastasis and drug resistance so that more(More)
Glioblastoma multiforme (GBM) is one of the most aggressive tumors in the central nervous system. SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. However, the function of SEMA6A in GBM is still undefined. In the present study, we investigated the expression of SEMA6A protein in 200 GBM(More)