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Genetical genomics experiments have now been routinely conducted to measure both the genetic markers and gene expression data on the same subjects. The gene expression levels are often treated as quantitative traits and are subject to standard genetic analysis in order to identify the gene expression quantitative loci (eQTL). However, the genetic(More)
For a prediction problem of a given target feature in a large causal network under external interventions, we propose in this paper two partial orientation and local structural learning (POLSL) approaches, Local-Graph and PCD-by-PCD (where PCD denotes Parents , Children and some Descendants). The POLSL approaches are used to discover the local structure of(More)
To detect goat vascular endothelial growth factor (VEGF)-mediated regrowth of hair, full-length VEGF164 cDNA was cloned from Inner Mongolia cashmere goat (Capra hircus) into the pET-his prokaryotic expression vector, and the recombinant plasmid was transferred into E. coli BL21 cells. The expression of recombinant 6×his-gVEGF164 protein was induced by 0.5(More)
For a given target node T and a given depth k ≥ 1, we propose an algorithm for discovering a local causal network around the target T to depth k. In our algorithm, we find parents, children and some descendants (PCD) of nodes stepwise away from the target T until all edges within the depth k local network cannot be oriented further. Our algorithm extends(More)
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