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Genome sequence and genetic diversity of the common carp, Cyprinus carpio
TLDR
A draft genome of domesticated C. carpio (strain Songpu) is presented, whose current assembly contains 52,610 protein-coding genes and approximately 92.3% coverage of its paleotetraploidized genome (2n = 100).
Genetic analysis of “all-fish” growth hormone gene trans ferred carp (Cyprinus carpio L.) and its F1 generation
TLDR
The genetic separation and the characteristic distribution of the F1 generation were genetically analyzed, which gave solid evidence for the hypothesis that 2–3 chromosomes are integrated with transgene.
The allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio
TLDR
Gen expression bias across surveyed tissues such that subgenome B is more dominant in homoeologous expression is found, and CG methylation in promoter regions may play an important role in altering gene expression in allotetraploid C. carpio.
Genome-Wide SNP Discovery from Transcriptome of Four Common Carp Strains
Background Single nucleotide polymorphisms (SNPs) have been used as genetic marker for genome-wide association studies in many species. Gene-associated SNPs could offer sufficient coverage in trait
An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio)
TLDR
The high-density and high-resolution genetic linkage map provides an important tool for QTL fine mapping and positional cloning of economically important traits, and improving common carp genome assembly.
miR-146a Attenuates Sepsis-Induced Myocardial Dysfunction by Suppressing IRAK1 and TRAF6 via Targeting ErbB4 Expression
TLDR
It is demonstrated that the overexpression of miR-146a mitigates myocardial injury by negatively regulating NF-κB activation and inflammatory cytokine production via targeting ErbB4 in LPS-induced sepsis.
Comparative Transcriptome Analysis Reveals the Genetic Basis of Skin Color Variation in Common Carp
TLDR
It is proposed that common carp skin pigmentation depends upon at least three pathways, including melanin biosynthesis, Wnt and MAPK signaling pathways and TYRP1, SILV, ASIP and xCT, which showed significant differences in their expression patterns between the two strains.
The allotetraploid origin and asymmetrical genome evolution of common carp Cyprinus carpio
TLDR
It is estimated that the two diploid progenitor species diverged approximately 23 million years ago and merged to form the allotetraploid C. carpio approximately 12.4 Mya, which likely correlated with environmental upheavals caused by the extensive uplift of the Qinghai-Tibetan Plateau.
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