Jianwen Xiao

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Medulloblastoma (MB) is the most common embryonal CNS tumor of childhood. Its survival rates have significantly improved over the years due to developments in diagnostic techniques and therapeutic strategies. However, it is still an important cause of cancer-related deaths in children. Extracellular matrix metalloproteinase inducer (EMMPRIN) is a member of(More)
OBJECTIVE To analyze the responses of pediatric patients with newly-diagnosed acute primary idiopathic thrombocytopenic purpura (ITP) to two distinct corticosteroids. METHODS We retrospectively reviewed a cohort of 259 patients with acute ITP diagnosed between 2004 and 2008. Specifically, we compared response rates and adverse effects in patients treated(More)
OBJECTIVE To investigate the incidence, clinical symptoms, signs and laboratory features of childhood hemophagocytic lymphohistiocytosis (HLH) in China. METHODS A retrospective study was performed on 217 pediatric patients with HLH who were admitted to Children's Hospital of Chongqing Medical University from January 2006 to April 2013. All(More)
Varicella is usually regarded as a benign and self-limited disorder. Severe cases, including hemorrhagic varicella, are rare. These cases were thought to be influenced by underlying diseases such as HIV infection, leukemia. This study aims to explore the relationship among clinical character, lab data and prognoses in children suffering from hemorrhagic(More)
OBJECTIVE To explore the risk factors, and control measures of cytomegalovirus (CMV) infection after hematopoietic stem cell transplantion (HSCT) in children with primary immunodeficiency diseases(PID). METHODS We retrospectively analyzed results of 26 patients with PID-Wiskott-Aldrich syndrome (WAS, n=20), severe combined immunodeficiency (SCID, n=1) ,(More)
OBJECTIVE To investigate the incidence and the gene mutation frequencies and patterns of α-thalassemia in preschool children in Chongqing city. METHODS Cluster random sampling was used. A total of 1057 preschool children in three areas of Chongqing were screened by using routine blood test and hemoglobin electrophoresis analysis. Molecular analysis(More)
OBJECTIVE To explore the clinical features, laboratory findings and treatment of infant leukemia. METHODS A retrospective analysis of the clinical data was performed of the cases with the diagnosis of infant acute leukemia from August 1993 to October 2014 in our hospital. RESULTS A total of 144 cases of infant leukemia were diagnosed in the defined(More)
Infectious disease is common in stem cell transplant recipients, especially in the patients of primary immunodeficiency disease (PID). However, there’s little report about sepsis and meningitis caused by enterococcus faecium (EF). Meningitis and sepsis caused by EF is uncommon in stem cell transplant recipients. We report a case of EF meningitis and sepsis(More)
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