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High-precision motion estimation has become essential in ultrasound-based techniques such as time-domain Doppler and elastography. Normalized cross-correlation (NCC) has been shown as one of the best motion estimators. However, a significant drawback is its associated computational cost, especially when RF signals are used. In this paper, a method based on(More)
The pulse-wave velocity (PWV) has been used as an indicator of vascular stiffness, which can be an early predictor of cardiovascular mortality. A noninvasive, easily applicable method for detecting the regional pulse wave (PW) may contribute as a future modality for risk assessment. The purpose of this study was to demonstrate the feasibility and(More)
The abdominal aortic aneurysm (AAA) is a common vascular disease. The current clinical criterion for treating AAAs is an increased diameter above a critical value. However, the maximum diameter does not correlate well with aortic rupture, the main cause of death from AAA disease. AAA disease leads to changes in the aortic wall mechanical properties. The(More)
BACKGROUND Arterial stiffening is recognized to be associated with increased cardiovascular mortality and to be a major cause of several cardiovascular complications. Pulse wave velocity (PWV) has been widely accepted to be a reliable and robust measure of arterial stiffness. In this article, the novel ultrasound-based pulse wave imaging (PWI) method is(More)
Noninvasive quantification of regional arterial stiffness, such as measurement of the pulse wave velocity (PWV), has been shown to be of high clinical importance. Pulse wave imaging (PWI) has been previously developed by our group to visualize the propagation of the pulse wave along the aorta and to estimate the regional PWV. The objective of this paper is(More)
Electromechanical Wave Imaging (EWI) is a non-invasive, ultrasound-based imaging method capable of mapping the electromechanical wave (EW) in vivo, i.e. the transient deformations occurring in response to the electrical activation of the heart. Optimal imaging frame rates, in terms of the elastographic signal-to-noise ratio, to capture the EW cannot be(More)
Arterial stiffness has been shown to be a good indicator of arterial wall disease. However, a single parameter is insufficient to describe the complex stress-strain relationship of a multi-component, non-linear tissue such as the aorta. We therefore propose a new approach to measure the stress-strain relationship locally in vivo noninvasively, and present a(More)
— Echocardiography is the most prevalent imaging modalities in clinical cardiology. However, current diagnostic techniques rely on qualitative image analysis, ignoring the quantitative data inherent to this modality. We seek to develop a quantitative system for analyzing echocardiographic images. In this study, the performance of Myocardial Elastography was(More)
High frame-rate ultrasound RF data acquisition has been proved to be critical for novel cardiovascular imaging techniques, such as high-precision myocardial elastography, pulse wave imaging (PWI), and electromechanical wave imaging (EWI). To overcome the frame-rate limitations on standard clinical ultrasound systems, we developed an automated method for(More)
Myocardial elastography is a novel method for noninvasively assessing regional myocardial function, with the advantages of high resolution and high precision. The purpose in this paper was to isolate the left ventricle from other structures for better displacement and strain visualization. Using a high-resolution (30 MHz) ultrasound system and a(More)