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China launched a Malaria Elimination Action Plan for 2010-2020. Yunnan, a province along the western border of China, belongs to the Great Mekong Subregion. Malaria elimination in the Great Mekong Region is a great challenge. We chose Yunnan to analyze the challenges for malaria elimination and how to overcome the barriers for malaria elimination globally.
Memory trace analysis is an important technology for architecture research, system software (i.e., OS, compiler) optimization, and application performance improvements. Many approaches have been used to track memory trace, such as simulation, binary instrumentation and hardware snooping. However, they usually have limitations of time, accuracy and capacity.(More)
Status epilepticus (SE) is a progressive and often lethal human disorder characterized by continuous or rapidly repeating seizures. Of major significance in the pathology of SE are deficits in the functional expression of GABA(A) receptors (GABA(A)Rs), the major sites of fast synaptic inhibition in the brain. We demonstrate that SE selectively decreases the(More)
BACKGROUND There are few large samples and single-center series that focus on the outcomes of pancreatic enucleation and risk factors for clinical pancreatic fistula (PF). This study aimed to evaluate the indications, short- and long-term results, and risk factors for clinical PF after pancreatic enucleation. METHODS Patients who underwent pancreatic(More)
BACKGROUND Accumulating evidence suggests the pro-inflammatory cytokine interleukin-6 (IL-6) in tumor microenvironment may promote the development of hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unknown. METHODS The expression and promoter activity of lncTCF7 were measured by quantitative real-time polymerase chain(More)
The Greater Mekong Subregion (GMS), comprised of six countries including Cambodia, China's Yunnan Province, Lao PDR, Myanmar (Burma), Thailand and Vietnam, is one of the most threatening foci of malaria. Since the initiation of the WHO's Mekong Malaria Program a decade ago, malaria situation in the GMS has greatly improved, reflected in the continuous(More)
Biodegradable polymers can serve as barriers to prevent the post-operative intestinal adhesion. Herein, we synthesized a biodegradable triblock copolymer poly(ɛ-caprolactone-co-lactide)-b-poly(ethylene glycol)-b-poly(ɛ-caprolactone-co-lactide) (PCLA-PEG-PCLA). The concentrated polymeric aqueous solution was injectable, and a hydrogel could be rapidly formed(More)
A large-deflection elasticity model was used to describe the mechanical behavior of cartilaginous tissues during three-point bending tests. Force-deflection curves were measured for 20-mm long x 4-mm wide x approximately 1-mm thick strips of porcine auricular and costal cartilage. Using a least-squares method with elastic modulus in bending as the only(More)
BACKGROUND Primary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific literature. METHODS PLMS cases reported in Chinese and(More)
The superiority of partial splenectomy (PS) as a treatment for benign tumors has not well been confirmed. This study aimed to identify the short- and long-term outcomes of PS, to compare laparoscopic and laparotomic PS, and to demonstrate whether the effects of PS are superior to that of total splenectomy (TS). Patients with either a hemangioma or cyst who(More)