Jianwei Leng

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OBJECTIVE To compare persistence and adherence to triple therapy with the nonbiologic disease-modifying antirheumatic drugs (DMARDs) methotrexate (MTX), hydroxychloroquine, and sulfasalazine, versus a tumor necrosis factor inhibitor (TNFi) plus MTX in patients with rheumatoid arthritis (RA). METHODS Administrative and laboratory data were analyzed for US(More)
Manually annotating clinical document corpora to generate reference standards for Natural Language Processing (NLP) systems or Machine Learning (ML) is a time-consuming and labor-intensive endeavor. Although a variety of open source annotation tools currently exist, there is a clear opportunity to develop new tools and assess functionalities that introduce(More)
The Health Insurance Portability and Accountability Act (HIPAA) Safe Harbor method requires removal of 18 types of protected health information (PHI) from clinical documents to be considered "de-identified" prior to use for research purposes. Human review of PHI elements from a large corpus of clinical documents can be tedious and error-prone. Indeed,(More)
PURPOSE Outpatient infusions are commonly missing in Veterans Health Affairs (VHA) pharmacy dispensing data sets. Currently, Healthcare Common Procedure Coding System (HCPCS) codes are used to identify outpatient infusions, but concerns exist if they correctly capture all infusions and infusion-related data such as dose and date of administration. We(More)
Fingerprint feature detection is one of the key techniques of automatic fingerprint identification. There are some problems of rotation and shift in the present fingerprint feature detection. This paper has given an algorithm of bifurcation detection based on neural network template matching. Correlative matching is to calculate the correlative value(More)
BACKGROUND The ShARe/CLEF eHealth challenge lab aims to stimulate development of natural language processing and information retrieval technologies to aid patients in understanding their clinical reports. In clinical text, acronyms and abbreviations, also referenced as short forms, can be difficult for patients to understand. For one of three shared tasks(More)
INTRODUCTION/OBJECTIVE Pulmonary function tests (PFTs) are objective estimates of lung function, but are not reliably stored within the Veteran Health Affairs data systems as structured data. The aim of this study was to validate the natural language processing (NLP) tool we developed-which extracts spirometric values and responses to bronchodilator(More)
Application of virtual reality is a promising technology that combines the virtual reality approach to advanced modeling, simulation and user interface techniques [1]. Power electronics is a vital subject in the electric engineering, and furthermore, hands-on experiment is an important component in the subject. In the experiment, students cannot see the(More)
OBJECTIVE To determine annual biologic drug and administration costs to the US Veterans Health Administration (VHA) per treated patient with rheumatoid arthritis (RA), psoriasis (PsO), psoriatic arthritis (PsA), or ankylosing spondylitis (AS) who received abatacept, adalimumab, certolizumab pegol, etanercept, golimumab, infliximab, rituximab, tocilizumab,(More)