Jianwei Jia

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Inflammatory cytokines and neurotrophins play crucial roles in hypoxic-ischemic brain damage (HIBD), but the expression changes of these proteins had not been systematically studied. In this article, we compared the levels of tumor necrosis factor alpha (TNF-α), intercellular adhesion molecule-1 (ICAM-1), interleukin 1beta (IL-1β), nerve growth factor(More)
The effect of mouse resistin on hepatic insulin resistance in vivo and in vitro, and its possible molecular mechanism were examined. Focusing on liver glycogen metabolism and gluconeogenesis, which are important parts of glucose metabolism, in primary cultures of rat hepatocytes we found that glycogen content was significantly lower (P<0.05) after treatment(More)
Drug-induced gene expression dataset (for example Connectivity Map, CMap) represent a valuable resource for drug-repurposing, a class of methods for identifying novel indications for approved drugs. Recently, CMap-based methods have successfully applied to identifying drugs for a number of diseases. However, currently few gene expression based methods are(More)
CONTEXT Primary dysmenorrhea is one of the most frequent gynecological disorders in young women. Chinese herbal medicine has the advantage in terms of multi-targeting efficacy, lower toxicity, as well as lower cost. Core licorice is the hard and atropurpureus heart part in root and rootstock of Glycyrrhiza uralensis Fisch (Leguminosae), having a therapeutic(More)
In the liver, glucokinase (GCK) facilitates hepatic glucose uptake during hyperglycemia and is essential for the regulation of a network of glucose-responsive genes involved in glycolysis, glycogen synthesis, and lipogenesis. To better understand the consequences of changes in response to a liver-specific deficiency of GCK function, we examined the(More)
Since the Shor algorithm showed that a quantum algorithm can efficiently calculate discrete logarithms and factorize integers, it has been used to break the RSA, EIGamal, and ECC classical public key cryptosystems. This is therefore a significant issue in the context of ensuring communication security over insecure channels. In this paper, we prove that(More)
Advances in quantum computation threaten to break public key cryptosystems that are based on the difficulty of factorization or the difficulty of discrete logariths, although, no quantum algorithms have been found to be able to solve certain mathematical problems on non-commutative algebraic structures up to now. The proposed new quasi-inverse based(More)
Advances in quantum computation threaten to break public key cryptosystems such as RSA, ECC, and ElGamal that are based on the difficulty of factorization or taking a discrete logarithm, although up to now, no quantum algorithms have been found that are able to solve certain mathematical problems on noncommutative algebraic structures. Against this(More)
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