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Pinch-3 protein is an important constituent of cell membranes, which directly affects the cell morphology and mechanical properties. We observed and compared the change of morphology and cell traction force of glomerular podocytes before and after Pinch-3 gene inhibition by gene interference technology in this experiment. We found that a number of pores… (More)
The paper presents a hybrid Broyden family method with global mesh refinement and high order discretization scheme because that this type methods are usually efficient and the high order discretization scheme could reduce the discretization error significantly. The method is then applied to pipeline isothermal simulation problems.