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The p53 gene plays an important role in cell cycle control in response to DNA damage, which may increase the probability of mutations that lead to carcinogenesis. The p53 codon 72 Arg right curved arrow Pro polymorphism has been suggested to be associated with risk for different kind of cancers, but the data on gastric cancer (GC) is very limited. To(More)
V.M. Abazov, B. Abbott, M. Abolins, B. S. Acharya, M. Adams, T. Adams, E. Aguilo, S. H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton,* G. Alverson, G.A. Alves, M. Anastasoaie, L. S. Ancu, T. Andeen, S. Anderson, M. S. Anzelc, M. Aoki, Y. Arnoud, M. Arov, M. Arthaud, A. Askew, B. Åsman, A. C. S. Assis Jesus, O. Atramentov, C. Avila, C. Ay, F. Badaud,(More)
Fluorescent reporters are useful in vitro and in vivo probes of protein structure, function, and localization. Here we report that the fluorescent amino acid, 3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid (Anap), can be site-specifically incorporated into proteins in mammalian cells in response to the TAG codon with high efficiency using an(More)
Mammalian cells are constantly exposed to a wide variety of genotoxic agents from both endogenous and exogenous sources. Genetic variability in DNA repair may contribute to human cancer risk. In this population-based case-control study in China, we tested the hypothesis that a C to T variant (Thr241Met) of DNA repair gene XRCC3 (X-ray repair(More)
The beef tapeworm Taenia saginata infects human beings with symptoms ranging from nausea, abdominal discomfort to digestive disturbances and intestinal blockage. In the present study, microRNA (miRNA) expressing profile in adult T. saginata was analyzed using Solexa deep sequencing and bioinformatics analysis. A total of 15.8 million reads was obtained by(More)
Abstmct-Jn this paper, an advanced hierarchical model has been proposed to produce a more effective character recognizer based on the probability of occurrence of the patterns. New definitions such as crucial parts, efficiency ratios, degree of confusion, similar character pairs, etc. have also been given to facilitate pattern analysis and character(More)
V.M. Abazov, B. Abbott, M. Abolins, B. S. Acharya, M. Adams, T. Adams, E. Aguilo, S. H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton,* G. Alverson, G.A. Alves, M. Anastasoaie, L. S. Ancu, T. Andeen, S. Anderson, B. Andrieu, M. S. Anzelc, Y. Arnoud, M. Arov, M. Arthaud, A. Askew, B. Åsman, A. C. S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C.(More)
Studies suggest that IL-1beta (encoded by IL-1B gene) is a pro-inflammatory cytokine and potent inhibitor of gastric acid secretion, which is proposed as a key determinant in gastric carcinogenesis. Two potentially functional polymorphisms (C-31T and T-511C) in the IL-1B promoter were suggested to be correlated with alteration of Helicobacter pylori(More)