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Differential expression analysis based on “next-generation” sequencing technologies is a fundamental means of studying RNA expression. We recently developed a multi-step normalization method (called TbT) for two-group RNA-seq data with replicates and demonstrated that the statistical methods available in four R packages (edgeR, DESeq, baySeq, and NBPSeq)(More)
RNA-seq is a powerful tool for measuring transcriptomes, especially for identifying differentially expressed genes or transcripts (DEGs) between sample groups. A number of methods have been developed for this task, and several evaluation studies have also been reported. However, those evaluations so far have been restricted to two-group comparisons.(More)
Nowadays, people usually depend on augmented reality (AR) systems to obtain an augmented view in a real-world environment. With the help of advanced AR technology (e.g. object recognition), users can effectively distinguish multiple objects of different types. However, these techniques can only offer limited degrees of distinctions among different objects(More)
The core circadian oscillator of cyanobacteria consists of three proteins, KaiA, KaiB, and KaiC. This circadian oscillator could be functionally reconstituted in vitro with these three proteins, and therefore has been a very important model in circadian rhythm research. KaiA can bind to KaiC and then stimulate its phosphorylation, but their interaction(More)
In this paper, we leverage RFID technology to label different objects with RFID tags, so as to realize the vision of "show me what I see from the augmented reality system". We deploy additional RFID antennas to the COTS depth camera and propose a continuous scanning-based scheme to scan the objects, i.e., the system continuously rotates and samples the(More)
The R/Bioconductor package, TCC, provides users with a robust and accurate framework to perform differential expression (DE) analysis of tag count data. We recently developed a multi-step normalization method (TbT; Kadota et al., 2012 [3]) for two-group RNA-seq data. The strategy (called DEGES) is to remove data that are potential differentially expressed(More)
—We consider the generalized differential entropy of normalized sums of independent and identically distributed (IID) continuous random variables. We prove that the Rényi entropy and Tsallis entropy of order α (α > 0) of the normalized sum of IID continuous random variables with bounded moments are con-vergent to the corresponding Rényi entropy and Tsallis(More)
—Sun et al (2008) developed a quasi-analytical pricing model for arithmetic Asian option bases on an approximate relationship between the geometric and arithmetic average of the log-normal random variable. We perform extensive numerical experiments to investigate the accuracy of the model. The numerical evidences show that the accuracy of the method depends(More)