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In their classic paper which demonstrated the preadaptive origin of phage resistance in bacteria, Luria and Delbriick (1943) proposed the use of the fluctuation test to estimate mutation rates in a bacterial population. Subsequently, a number of investigators have examined this problem from various angles, including formal 1980), all dealing with the(More)
The factors that affect reliable estimations of mutation rates (mu) in cultured mammalian somatic cell populations by fluctuation analysis are studied experimentally and statistically. We analyze the differential effect of the final cell population size in each culture (Nt) and the number of parallel cultures (C) on the variation in the rate estimates (mu)(More)
Maize is exposed to the combined stresses of water deficiency and soil salinity within its natural habitat, particularly in irrigated and dry land agricultural areas. Hence, the effect of these combined stresses on the metabolic response of maize plants was determined to improve understanding of stress tolerance mechanisms of maize in the field. Maize(More)
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