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In this paper, we develop the nonsubsampled contourlet transform (NSCT) and study its applications. The construction proposed in this paper is based on a nonsubsampled pyramid structure and nonsubsampled directional filter banks. The result is a flexible multiscale, multidirection, and shift-invariant image decomposition that can be efficiently implemented(More)
This study presents PKSolver, a freely available menu-driven add-in program for Microsoft Excel written in Visual Basic for Applications (VBA), for solving basic problems in pharmacokinetic (PK) and pharmacodynamic (PD) data analysis. The program provides a range of modules for PK and PD analysis including noncompartmental analysis (NCA), compartmental(More)
To better understand the evolution of allopolyploids, 4 different combinations between wheat (Triticum aestivum L.) and rye (Secale cereale L.) including 12 F1 hybrids and 12 derived amphiploids were analyzed and compared with their direct parental plants by PCR analysis using 150 wheat SSR (single sequence repeat) markers and by FISH analysis using a(More)
In this paper we study the nonsubsampled contourlet transform. We address the corresponding filter design problem using the Mc-Clellan transformation. We show how zeroes can be imposed in the filters so that the iterated structure produces regular basis functions. The proposed design framework yields filters that can be implemented efficiently through a(More)
CLCF-1 is a cytokine known for B-cell stimulation and for neurotrophic properties. We have identified CLCF-1 as a potential injurious factor in the human renal disease focal segmental glomerulosclerosis (FSGS). We investigated its effects on renal cells and renal function in in vitro and in vivo studies. Methods include measurement of the effect of CLCF-1(More)
Inactivating mutations of the PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) endopeptidase, the disease-causing gene in X-linked hypophosphatemia (XLH), results in increased circulating levels of fibroblastic growth factor-23 (FGF23), a bone-derived phosphaturic factor. To determine the causal role of FGF23 in XLH, we(More)
The regulation of the phosphaturic factor fibroblast growth factor 23 (FGF23) is not well understood. It was found that administration of 1,25-dihydroxyvitamin D(3) (1,25[OH](2)D(3)) to mice rapidly increased serum FGF23 concentrations from a basal level of 90.6 +/- 8.1 to 213.8 +/- 14.6 pg/ml at 8 h (mean +/- SEM; P < 0.01) and resulted in a four-fold(More)
In recent years, several mathematical models have been developed for analysis of drug dissolution data, and many different mathematical approaches have been proposed to assess the similarity between two drug dissolution profiles. However, until now, no computer program has been reported for simplifying the calculations involved in the modeling and(More)
OBJECTIVE To evaluate the effect of preoperative transarterial chemoembolization (TACE) for resectable large hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA Resection of HCC is potentially curative, but local recurrence is very common. There is currently no effective neoadjuvant or adjuvant therapy. METHODS From July 2001 to December 2003, 108(More)
We present the nonsubsampled contourlet transform and its application in image enhancement. The nonsubsampled contourlet transform is built upon nonsubsampled pyramids and nonsubsampled directional filter banks and provides a shift-invariant directional multiresolution image representation. Existing methods for image enhancement cannot capture the geometric(More)