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INVITED REVIEW: Microbial ecology in the age of genomics and metagenomics: concepts, tools, and recent advances
- Jianping Xu
- BiologyMolecular ecology
- 1 June 2006
The use of four specific genomics methods in analysing the diversity and potential activity of microbial populations and communities from a variety of terrestrial and aquatic environments are highlighted and the ecological implications are briefly discussed.
Quantitative variation of biofilms among strains in natural populations of Candida albicans.
The results demonstrated that natural clones and clonal lineages of C. albicans exhibited extensive quantitative variation in biofilm formation, and was positively correlated with cell surface hydrophobicity.
Clonal Expansion and Emergence of Environmental Multiple-Triazole-Resistant Aspergillus fumigatus Strains Carrying the TR34/L98H Mutations in the cyp51A Gene in India
The results are consistent with the hypothesis that exposure of A. fumigatus to azole fungicides in the environment causes cross-resistance to medical triazoles and emphasises the need of continued surveillance of resistance in environmental and clinical Aspergillosis strains.
Genome sequence of the button mushroom Agaricus bisporus reveals mechanisms governing adaptation to a humic-rich ecological niche
Observations reveal genetic and enzymatic mechanisms governing adaptation to the humic-rich ecological niche formed during plant degradation, further defining the critical role such fungi contribute to soil structure and carbon sequestration in terrestrial ecosystems.
Comparative Gene Genealogies Indicate that Two Clonal Lineages of Cryptococcus gattii in British Columbia Resemble Strains from Other Geographical Areas
The results indicate that the C. gattii population in B.C. comprises at least two divergent lineages, corresponding to previously identified VGI and VGII molecular types.
Fundamentals of fungal molecular population genetic analyses.
- Jianping Xu
- BiologyCurrent issues in molecular biology
- 1 July 2006
This paper provides an overview of the molecular techniques and the basic analytical tools used to address various fundamental population and evolutionary genetic questions in fungi.
Emergence of Azole-Resistant Aspergillus fumigatus Strains due to Agricultural Azole Use Creates an Increasing Threat to Human Health
Multi-azole resistance in A. fumigatus due to the TR34/L98H mutations has become an emerging problem in both Europe and Asia and has been associated with high rates of treatment failures.
A Trojan horse mechanism of bacterial pathogenesis against nematodes
- Qiuhong Niu, Xiaowei Huang, Ke-Qin Zhang
- BiologyProceedings of the National Academy of Sciences
- 23 August 2010
It is shown that the bacterium Bacillus nematocida B16 lures nematodes by emitting potent volatile organic compounds that are much more attractive to worms than those from ordinary dietary bacteria.
Molecular epidemiology of candidemia: evidence of clusters of smoldering nosocomial infections.
- L. R. Ásmundsdóttir, H. Erlendsdóttir, G. Haraldsson, Hong Guo, Jianping Xu, M. Gottfredsson
- Medicine, BiologyClinical infectious diseases : an official…
- 15 July 2008
In an unselected patient population, as many as one-third of all cases of candidemia may be attributable to nosocomial clusters, and the risk is dependent on hospital wards and patient populations; it is highest in intensive care units.
Geographic Distribution of Mating Type Alleles of Cryptococcus neoformans in Four Areas of the United States
The results suggest that the environment in San Francisco might contain Aa strains capable of mating with Dα strains, and demonstrate that the sample from San Francisco had a significantly higher proportion of self-fertile strains than those from the other three areas.