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OBJECTIVE The ligand EphrinB2 and the corresponding receptor EphB4 are up-regulated and involved in tumour growth in various human cancers. However, little is known about how this receptor-ligand complex contributes to the progression of glioma. This prompted us to study the association between the expressions of EphrinB2 and EphB4, clinicopathological(More)
This paper presents an approach to enhance speech feature estimation in the log spectral domain under noisy environments. A higher-order switching linear dynamic model (SLDM) is explored as a parametric model for the clean speech distribution, which enforces a state transition in the feature space and captures the smooth time evolution of speech conditioned(More)
BACKGROUND & AIM Human kinesin superfamily proteins (KIFs) are a conserved class of microtubule-dependent molecular motor proteins with adenosine triphosphatase activity and motion characteristics. As a member of KIFs, KIF14 plays an important role in the regulation of cell cycle and mitotic progression. Deregulation of KIF14 has been found in several human(More)
CD24 is overexpressed in glioma cells in vitro and in vivo. However, the correlation of its expression with clinicopathological parameters of gliomas and its prognostic significance in this tumor remain largely unknown. To address this problem, 151 glioma specimens and 10 nonneoplastic brain tissues were collected. Quantitative real-time PCR,(More)
OBJECTIVE To investigate the distribution and effects of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and its isoforms in bladder, especially in bladder interstitial cells of Cajal (ICC). METHODS Four HCN isoforms were detected in bladder tissue from rats using reverse transcription-polymerase chain reaction and Western blotting. The(More)
OBJECTIVE To investigate the expression and function of T-type calcium channels in the interstitial cells of Cajal in rat bladders. METHODS Bladders were harvested from Sprague-Dawley rats. The expression of T-type calcium channels subtypes (α1G, α1H, and α1I) in interstitial cells of Cajal were identified by double-labeled immunofluorescence analysis and(More)
Recent genome-wide association studies (GWAS) that focus on childhood acute lymphoblastic leukemia (ALL), the most common malignancy in children younger than 15 years old, have found evidence that single nucleotide polymorphisms (SNPs) in IKZF1 (7p12.2), ARID5B (10q21.2) and CEBPE (14q11.2) are strongly related to the risk of childhood ALL. These(More)
This letter presents a new approach to enhance speech feature estimation in the log spectral domain under noisy environments. A mixture of linear dynamic models with an architecture similar to the so-called mixture of experts (ME) is investigated to describe the clean speech feature distribution parametrically. Switching Kalman filters are adapted to the(More)
— This paper presents an approach to enhance speech feature estimation in the log spectral domain under additive noise environments. A switching linear dynamic model (SLDM) is explored as a parametric model for the clean speech distribution, enforcing a state transition in the feature space and capturing the smooth time evolution of speech conditioned on(More)