Jianpeng Wang

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Genomic recombination requires cutting, processing, and rejoining of DNA by endonucleases, polymerases, and ligases, among other factors. We have proposed that DNA recombination mechanisms may contribute to long-term memory (LTM) formation in the brain. Our previous studies with the nucleoside analog 1-beta-D-arabinofuranosylcytosine triphosphate (ara-CTP),(More)
We examined the hypothesis that processes related to DNA recombination and repair are involved in learning and memory. Rats received intracerebroventricular (i.c.v.) infusions of the antimetabolite 1-beta-D-arabinofuranosylcytosine triphosphate (ara-CTP) or its precursor cytosine arabinoside (ara-C) 30 min prior to conditioned taste aversion (CTA) training.(More)
To label proteins covalently, one faces a trade-off between labeling a protein specifically and using a small tag. Often one must compromise one parameter for the other or use additional components, such as an enzyme, to satisfy both requirements. Here, we report a new reaction that covalently labels proteins by using engineered coiled-coil peptides.(More)
Mesoporous materials have recently gained much attention owing to their large surface area, narrow pore size distribution, and superior pore structure. These materials have been demonstrated as excellent solid supports for immobilization of a variety of proteins and enzymes for their potential applications as biocatalysts in the chemical and pharmaceutical(More)
Multienzyme complexes are of paramount importance in biosynthesis in cells. Yet, how sequential enzymes of cascade catalytic reactions synergize their activities through spatial organization remains elusive. Recent development of site-specific protein-nanoparticle conjugation techniques enables us to construct multienzyme assemblies using nanoparticles as(More)
Specific protein-peptide interactions are prevalent in the living cells and form a tightly regulated signaling network. These interactions, many of which have structural information revealed, provide ideal templates for affinity-guided covalent bioconjugation. Here we report the development of a set of four new reactions that covalently and(More)
A class of wideband microstrip-to-microstrip vertical transitions is proposed via multiresonant modes in a slotline resonator formed on their common ground plane. The slot acts as a multimode resonator with microstrip lines at its two sides as the input and output terminals. Multiresonant modes in this slotline resonator can be properly excited by setting a(More)
A new microstrip ultra-wideband (UWB) bandpass filter (BPF) with dual sharply rejected notched bands based on E-shaped resonator is proposed in this letter. The basic UWB BPF is designed using interdigital coupled lines and rectangular patch multiple-mode resonator (MMR). Then, the resonance properties of the E-shaped resonator are studied. The analyzed(More)
—A new microstrip ultra-wideband (UWB) bandpass filter (BPF) with triple-notched bands is presented in this paper. The circuit topology and its corresponding electrical parameters of the initial microstrip UWB BPF are desired by a variation of genetic algorithm (VGA). Then, triple-notched bands inside the UWB passband are implemented by coupling a square(More)
Polyhistidine peptide dendrimer self-assembles on CdSe/ZnS quantum dots (QDs) with very high affinity and stability, a property ascribable to its multivalent geometry. Here we designed a fluorescent protein, GCN-mCherry, that exists as an oligomeric bundled structure in solution as well as on the surface to imitate the structure of a synthetic dendrimer.(More)