Jianling Yang

Learn More
[1] Following an El Niño event, a basin-wide warming takes place over the tropical Indian Ocean, peaks in late boreal winter and early spring, and persists through boreal summer. Our observational analysis suggests that this Indian Ocean warming induces robust climatic anomalies in the summer Indo-West Pacific region, prolonging the El Niño's influence(More)
Activation of eIF4B correlates with Abl-mediated cellular transformation, but the precise mechanisms are largely unknown. Here we show that eIF4B is a convergent substrate of JAK/STAT/Pim and PI3K/Akt/mTOR pathways in Abl transformants. Both pathways phosphorylated eIF4B in Abl-transformed cells, and such redundant regulation was responsible for the limited(More)
PURPOSE To investigate the profile and determinants of retinal optical intensity in normal subjects using 3D spectral domain optical coherence tomography (SD OCT). METHODS A total of 231 eyes from 231 healthy subjects ranging in age from 18 to 80 years were included and underwent a 3D OCT scan. Forty-four eyes were randomly chosen to be scanned by two(More)
Hepatitis C virus (HCV) infection is characterized by a strong propensity toward chronicity. During chronic HCV infection, HCV core protein is implicated in deregulating cytokine expression that associates with chronic inflammation. A20 is known as a powerful suppressor in cytokine signaling, in this study, we explored the A20 expression in macrophages(More)
PURPOSE To assess the correlation and agreement between the Topcon built-in algorithm and our graph-based algorithm in measuring the total and regional macular thickness for normal and glaucoma subjects. METHODS A total of 228 normal eyes and 93 glaucomatous eyes were enrolled in our study. All patients underwent comprehensive ophthalmic examination and(More)
  • 1