Jianling Yang

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Activation of eIF4B correlates with Abl-mediated cellular transformation, but the precise mechanisms are largely unknown. Here we show that eIF4B is a convergent substrate of JAK/STAT/Pim and PI3K/Akt/mTOR pathways in Abl transformants. Both pathways phosphorylated eIF4B in Abl-transformed cells, and such redundant regulation was responsible for the limited(More)
PURPOSE To assess the correlation and agreement between the Topcon built-in algorithm and our graph-based algorithm in measuring the total and regional macular thickness for normal and glaucoma subjects. METHODS A total of 228 normal eyes and 93 glaucomatous eyes were enrolled in our study. All patients underwent comprehensive ophthalmic examination and(More)
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