Jianjun Yan

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Hyperlipidemia plays a crucial role in the development and progression of coronary artery disease (CAD). Recent studies have identified that microRNAs (miRNAs) are important regulators of lipid metabolism, but little is known about the circulating levels of lipometabolism-related miRNAs and their relationship with the presence of CAD in patients with(More)
Digital auscultation of Traditional Chinese Medicine (TCM) is a relatively new technology which has been developed for several years. This system makes diagnoses by analyzing sound signals of patients using signal processing and pattern recognition. The paper discusses TCM auscultation in both traditional and current digital auscultation methods. First,(More)
AIM To determine the effects of the centrally antihypertensive drug moxonidine injected into the rostral ventrolateral medulla (RVLM) on baroreflex function in spontaneously hypertensive rats (SHR). METHODS Baroreflex sensitivity control of renal sympathetic nerve activity (RSNA) and barosensitivity of the RVLM presympathetic neurons were determined(More)
Numerous researchers have taken the solid step forward towards the objectification research of Traditional Chinese Medicine (TCM) four diagnostic methods. However, it is deficient in studies on information fusion of the four diagnostic methods. We establish four-diagnosis syndrome differentiation model of TCM based on information fusion technology. The(More)
Auscultation signals are nonstationary in nature. Wavelet packet transform (WPT) has currently become a very useful tool in analyzing nonstationary signals. Sample entropy (SampEn) has recently been proposed to act as a measurement for quantifying regularity and complexity of time series data. WPT and SampEn were combined in this paper to analyze(More)
Visfatin, a pro-inflammatory cytokine predominantly released from leucocytes, is correlated with coronary artery disease (CAD). We have previously reported that the −1535C>T polymorphism (rs1330082), which located on the promoter region of visfatin, was associated with decreased risk of CAD. Here, we investigated the underlying mechanism by which this(More)
This study aims at utilising Wavelet Packet Transform (WPT) and Support Vector Machine (SVM) algorithm to make objective analysis and quantitative research for the auscultation in Traditional Chinese Medicine (TCM) diagnosis. First, Wavelet Packet Decomposition (WPD) at level 6 was employed to split more elaborate frequency bands of the auscultation(More)