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Marriage is a major source of social support and a predictor of health; however, marriages that involve people with epilepsy are more likely to fail. To explore this issue in China, we compared the marital adjustment of patients with epilepsy to control subjects using the Dyadic Adjustment Scale (DAS). A total of 136 married persons with epilepsy and 145(More)
PURPOSE Data about super-refractory status epilepticus (SRSE) are scarce. This study aimed to assess the clinical features and outcome of patients with SRSE. METHOD Clinical features of all SRSE patients admitted to the Neurologic Intensive Care Unit (NICU)/Neurology Department of West China Hospital, Sichuan University, between January 2010 and August(More)
Epilepsy threatens the health of more than 50 million people all over the world. Many patients with epilepsy, especially temporal lobe epilepsy, are resistant to the current therapeutic drugs. Different strategies for these patients are therefore necessary to achieve maximum therapeutic effect. Neuromodulation techniques have gained widespread attention due(More)
The aim of this study was to better understand social support in adult people with epilepsy (PWE) in China and to explore the factors related to weaker or stronger social support in PWE when compared with a group of matching healthy controls. Consecutively, we recruited PWE from the epilepsy outpatient clinic of the West China Hospital and healthy controls(More)
Iron-sulfur (Fe-S) clusters are ubiquitous cofactors essential to various cellular processes, including mitochondrial respiration, DNA repair, and iron homeostasis. A steadily increasing number of disorders are being associated with disrupted biogenesis of Fe-S clusters. Here, we conducted whole-exome sequencing of patients with optic atrophy and other(More)
PURPOSE This study aimed to determine factors that influence the quality of life (QOL) of seizure-free adult patients with epilepsy in western China and address whether these determinants vary by antiepileptic drug (AED) withdrawal. METHODS A cross-sectional study was conducted in the epilepsy outpatient clinic of West China Hospital, Sichuan University.(More)
Smoking has a negative effect on most diseases, yet it is under-investigated in people with epilepsy; thus its role is not clear in the general population with epilepsy. We performed a retrospective pilot study on males with epilepsy to determine the smoking rate and its relationship with seizure control using univariate analysis to calculate odds ratios(More)
PURPOSE This study was conducted to survey the driving status of PWE in West China and to explore the sociodemographic and clinical factors associated with driving. METHODS Between October 2012 and October 2013, all adult patients who came to our epilepsy clinic in the West China Hospital were invited to participate. Logistic regression was used to detect(More)
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