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OBJECTIVE Dapagliflozin is a highly selective, orally active inhibitor of renal sodium-glucose cotransporter 2 that reduces hyperglycemia by increasing urinary glucose excretion. The goal of this study was to evaluate dapagliflozin as monotherapy in drug-naive Asian patients with type 2 diabetes whose disease was inadequately controlled with diet and(More)
This system focuses on a location-aware computing application and environment which provide preemptive information on dangerous locations in the kid's surroundings; i.e., the system alerts a kid on the move of the possible dangers whenever he/she is near accident prone areas. Using satellite-based GPS position sensing, this system can gradually learn and(More)
Cerebral perfusion x-ray computed tomography (PCT) imaging, which detects and characterizes the ischemic penumbra, and assesses blood-brain barrier permeability with acute stroke or chronic cerebrovascular diseases, has been developed extensively over the past decades. However, due to its sequential scan protocol, the associated radiation dose has raised(More)
Red-crowned cranes (Grus japonensis) were classified as an endangered species by the International Union for Conservation of Nature, but recently, their population has decreased dramatically. For the purpose of conserving this endangered species, 18 microsatellite markers were developed, including 12 newly isolated ones from a genomic library and 6 modified(More)
The rapid development of the Internet and the Internet of Things accelerates the emergence of the hyper world. It has become a pressing research issue to realize the organic amalgamation and harmonious symbiosis among humans, computers, and things in the hyper world, which consists of the social world, the physical world, and the information world (cyber(More)
AIM This study was designed to determine the effect of exenatide on inflammatory and oxidative stress markers in type 2 diabetes mellitus (T2DM) patients who were suboptimally controlled with metformin and/or sulfonylurea. SUBJECTS AND METHODS Twenty-three patients with T2DM with inadequate glucose control were randomly divided into two groups: exenatide(More)
Bayesian approaches, or maximum a posteriori (MAP) methods, are effective in providing solutions to ill-posed problems in image reconstruction. Based on Bayesian theory, prior information of the target image is imposed on image reconstruction to suppress noise. Conventionally, the information in most of prior models comes from weighted differences between(More)
Neuroinflammation has been recognized to play a critical role in the pathogenesis of Alzheimer's disease (AD), which is pathologically characterized by the accumulation of senile plaques containing activated microglia and amyloid β-peptides (Aβ). In the present study, we examined the neuroprotective effects of hydrogen sulfide (H2S) on neuroinflammation in(More)
— A cyber world (CW) is a digitized world created on cyberspaces inside computers interconnected by networks including the Internet. a smart world (SW) created on both cyberspaces and real spaces. It is mainly characterized by ubiquitous intelligence or computational intelligence pervasion in the physical world filled with smart things. In recent years,(More)
Insulin resistance (IR) plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS) which is a common disorder in premenopausal women. The association between the single nucleotide polymorphisms (SNPs) of insulin receptor substrate (IRS) gene and PCOS in several populations has been studied, but the results are conflicting. The aim of(More)